SEMICARBAZIDE HYDROCHLORIDE AR
One preparation method involves reacting carbon monoxide with hydrazine at superatmospheric pressures and at temperatures in the range from 0° C. to 200° C. and in the presence of a catalytic amount of a metal carbonyl to obtain semicarbazide which was acidified to yield the desired salt.
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Description
One preparation method involves reacting carbon monoxide with hydrazine at superatmospheric pressures and at temperatures in the range from 0° C. to 200° C. and in the presence of a catalytic amount of a metal carbonyl to obtain semicarbazide which was acidified to yield the desired salt.
Application
Semicarbazide hydrochloride is a general reagent used to synthesize semicarbazones from aldehydes and ketones. It can be used to build a variety of heterocyclic compounds, some of which are potent antimicrobial and antiviral agents. It can also be used to prepare corrosion inhibitors.
Notes
Semicarbazide Hydrochloride can affect you when breathed in. * Contact can irritate the skin and eyes. * High or repeated exposure may damage the nerves causing weakness, "pins and needles," and poor coordination in arms and legs.
Procedure
When semicarbazide reacts with a ketone(or aldehyde) to form semicarbazone. Only one nitrogen atom of semicarbazide acts as a nucleophile and attack the carbonyl carbon of the ketone. The product of the reaction consequently is R2C = N - NH - CONH2 rather than R2C = NCONH - NH2 .
Other names
SEMICARBAZIDE HYDROCHLORIDE AR
Packing & supply
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