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D-Serin

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Raw Chemicals-19
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D-Serine is a non-essential amino acid and dextro isomer of serine with antipsychotic activity

Product Description: 

D-Serine is a non-essential amino acid and dextro isomer of serine with antipsychotic activity. D-serine is a selective full agonist at the glycine site of N-methyl-D-aspartate (NMDA)-type glutamate receptor. Hypofunction of NMDA type of neurotransmission is believed to play a major role in pathophysiology of schizophrenia, therefore, administration of D-serine and subsequent activation of NMDA receptors may alleviate psychotic tendencies.

Product Application: 

D-Serine is involved in the biosynthesis of purines, pyrimidines, and other amino acids. D-Serine also is an agonist of glycine site of the NMDA-type glutamate receptor. It also acts as Lacosamide intermediate.

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Product Technical Specification: 

 

Colour                                                                                                       White to off-white  
Appearance (Form)  Crystalline compound
Solubility (Turbidity) 10% solution 2N HCl  Clear                                                         
Assay min. 99%
Specific rotation [a] -13° to -14° (C=5 , 5N HCl)
Loss on drying max. 0.3%
Sulphated Ash  max. 0.1%
Iron (Fe)  max. 0.001%
Heavy Metals (Pb)  max. 0.001%
Homogeneity by TLC  Passes test
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Product alias: 
<p> D-serine, (R)-2-amino-3-hydroxypropanoic acid(2R)-2-amino-3-hydroxypropanoic acid</p>

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Remarks: 

 

CAS Number     312-84-5   
Synonyms    NSC 77689 (R)-Serine
Molecular Formula                                                          C3H7NO3
Formula Weight 105.1
Purity ≥95%
Formulation  A solid
Solubility PBS 5 mg/mL
pH  7.2